Search on: MAP KINASE KINASE 4 
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Descriptor English:   MAP Kinase Kinase 4 
Descriptor Spanish:   MAP Quinasa Quinasa 4 
Descriptor Portuguese:   MAP Quinase Quinase 4 
Synonyms English:   JN Kinase Kinase
JNK Kinase
JNK-Activating Protein Kinase
JNKK1 Protein Kinase
Jun Amino-Terminal Kinase Kinase
MEK4 Protein Kinase
Mitogen-Activated Protein Kinase Kinase 4
SAP Kinase Kinase 1
SAP Kinase-Extracellular Signal-Regulated Kinase Kinase 1
SAPK-ERK Kinase 1
SEK1 Protein Kinase
Stress-Activated Protein Kinase Kinase 1
JNK Activating Protein Kinase
Jun Amino Terminal Kinase Kinase
Kinase, JNKK1 Protein
Mitogen Activated Protein Kinase Kinase 4
Protein Kinase, JNK-Activating
Protein Kinase, JNKK1
Protein Kinase, MEK4
Protein Kinase, SEK1
SAP Kinase Extracellular Signal Regulated Kinase Kinase 1
SAPK ERK Kinase 1
Stress Activated Protein Kinase Kinase 1  
Tree Number:   D08.811.913.696.620.682.700.565.400
D08.811.913.696.620.682.725.200.400
D12.644.360.440.400
D12.776.476.440.400
Definition English:   A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES and the RETINOID X RECEPTORS. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to cellular stress. 
History Note English:   2005(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38723 
Unique Identifier:   D048670 

Occurrence in VHL:
 

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